She has won numerous national journalism and book awards. In 2003, her story of a Honduran boy's struggle to find his mother in the US, entitled Enrique's Journey, won more than a dozen awards, among them the Pulitzer Prize for Feature Writing.
Expanded into a book, Enrique's Journey immediately became a national best-seller and won two major book awards. It was named one of the best books of the year by the Washington Post, San Francisco Chronicle, People, the Miami Herald, and the San Antonio Express-News. It has been translated into eight languages, and in 2010, Enrique's Journey was the second most chosen book for campus reads at universities across the country.
In 1998, Nazario was a Pulitzer Prize finalist for a series on children of drug-addicted parents. In 1994, she won a George Polk Award for Local Reporting for a series about hunger among school children in California.
Nazario, who grew up in Kansas and in Argentina, has written extensively from Latin America and about Latinos in the United States. She began her career at the Wall Street Journal, where she reported from four bureaus: New York, Atlanta, Miami, and Los Angeles.